Toxicity of aqueous crude neem leaf extract against culex mosquitoes

Prevention of mosquitoes from biting is one of the major problems in the world. Mosquitoes transmitting serious human diseases and causing millions of death every year. The repeated use of synthetic insecticides to control mosquitoes has created resistance to vectors and adverse environmental effects in addition to high operational cost. Many natural products have been reported as insect antifeedants or repellents. Azadirachta indica contains several active ingredients that are toxic to insects and are safety to the environment. The safety evaluation of different parts of neem preparations were made and used as an alternative insecticide in many parts of the world. In the present study aqueous crude neem leaf extract shows 30% and 70% mortality rate of mosquitoes for 6 h and 12 h, respectively. The present study was carried out to determine the efficacy of neem extract against culex mosquitoes in laboratory studies and field evaluation.