FORMULATION AND EVALUTION OF RAPIDLY DISSOLVING BUCCAL PATCHES

The objective of the present study was to formulate and evaluate the rapidly dissolving films. The main aim of the work is rapid disintegration and dissolution of the drug Etophylline, which is a bronchodilator used in treatment of asthma. Many pharmaceutical dosage are administered in the form of pills, granules, powers and liquids generally, a pill design is for swallowing intact or chewing to deliver a precise dosage of medication to patients. The pills, which include tablets and capsules, are able to retain their shapes under moderate pressure. However, some patient’s particularly pediatric and geriatric patients and also the unconscious patients have difficulty swallowing or chewing solid dosage form. Many pediatric and geriatric patients are unwilling to the take this solid preparations due to fear of choking. In order to assist these patients, several fast-dissolving drug delivery system have been developed Some of the drugs even take a very long time to dissolve, therefore the drug even take much longer time to show its activity, hence our work is aimed to fast dissolution of the drug and maximum bioavailability of bronchodilator Etophylline drug by forming a thin films which are administered orally.