SPECTROPHOTOMETRIC ESTIMATION OF SPARFLOXACIN IN BULK AND PHARHARMACEUTICAL DOSAGE FORMS

Two simple and sensitive visible Spectrophotometric methods [I and II] have been developed for the quantitative estimation of Sparfloxacin in bulk and Pharmaceutical dosage forms. Method-Iis based on ion-pair complex formation between Sparfloxacin and Bromocresol purple, which shows yellow color and gives maximum absorption at 410.0 nm and obeys Beer’s law in the concentration range of 5-25 μg/ml. Method-II is based on ion-pair complex formation between Sparfloxacin and Bromocresol green, which shows yellow color and gives maximum absorption at 420.0 nm and obeys Beer’s law in the concentration range of 5-25 μg/ml.