Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat

Background: Biochemical, haematological and Immunomodulatory effect of Ocimum sanctum in rat was studied. Objective: To evaluate the immunomodulatory effect of Ocimum sanctum in rat Methods: Aqueous extract of Ocimum sanctum were administered oraly at doses of 100, 200 mg/kg/day for 45 days in wistar albino rats. Immunomodulatory effect and biochemical and haematological changes were tested by standard methods. Results: Aqueous extract of the Ocimum sanctum showed increasing antibody production in dose dependent manner. It enhance the production of RBC, WBC and haemoglobin. It dose not affect the biochemical parameters. Conclusion: An oral administration of the aqueous extract of O. sanctum showed immunomodulatory effect in rat.