TO INVESTIGATE THE ACTION OF GINGER-JUICE ZINGIBER OFFICINALE ROSCOE (ZINGIBERACEAE) ON BLOOD COAGULATION PROCESS.

Investigation of ginger-juice (zingiber officinale roscoe) action on blood coagulation process in rat. Methods: (A) Albino Wister rats (n=6-12) were administered G.J at two doses (2ml & 4 ml/rat, p.o) as single administration and chronic treatment over period of 30 days. Following this assessment was done for possible effects on the blood coagulation. Parameters used during assessment were on the bleeding time, clotting time. prothrombin time, thrombin time, partial thromboplastin with kaolin (PTTk) and platelet count. Results: Chronicadministration of G.J (2ml & 4ml/rat, p.o) caused an increase in the bleeding time. There is no effect of gingerjuice treatment (2ml & 4ml/rat, p.o) for 30 days on the clotting time, prothrombin time, thrombin time, partial thromboplastin time with kaolin (PTTk), and Platelet counts. Conclusion: Ginger administration increasedbleeding time on chronic administration G.J in two different doses.