Screening of Some Extracts from Garcinia parvifolia Miq. (Guttiferae) for Antiplasmodial, Antioxidant, Cytotoxic and Antibacterial Activities

Crude extracts of some parts of Garcinia parvifolia Miq: root, stem bark, fruit and leaf, can be dissolved in various solvents, such as n-hexane, ethylacetate and methanol. The crude extracts of these plant parts were screened for antiplasmodial, antioxidant, cytotoxic and antibacterial activities. Most extracts show antiplasmodial activity but the extracts of roots and stem bark show strong antiplasmodial activities (IC50 7.88 and 4.11 μg mL-1). All of the extracts show antioxidant activities with IC50 <100 μg mL-1. They all show cytotoxic activity with a value of LC50 <1000 μg mL-1. N-hexane extract of leaf and fruit do not show antibacterial activity, while n-hexane and ethylacetae extracts of stem bark, root and fruit show strong antibacterial activity, especially against Staphyloccocus aureus.