Non Invasive Surfactant Application

Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration. Non-invasive techniques of respiratory support were developed in order to reduce the adverse effects associated with ventilation via an endotracheal tube. Noninvasive surfactant administration technique during spontaneous breathing along with nasal continous positive airway pressure support successfully reduces the need for further respiratory support and bronchopulmonary dysplasia rate in very low birth weight infants. Here we reviewed the new approches ton surfactant administration. [Archives Medical Review Journal 2013; 22(4.000): 634-644]