Down Syndrome: advances and perspectives

The Down Syndrome (DS) is a chromosomal disease characterized by expression of gene’s copy presents in chromosome 21 in triplicate. Is estimable that the incidence of DS is in the order of 1 in each 600/800 newborn babies and an average with 8000 new cases in Brazil. With basis in this information is verified that the continual need to know the natured of the individuals with Down syndrome as well the advances obtained by the science which is contributing for a larger extension in their lives. This article will expose some molecular mechanisms of DS, genetic and physiologic interactions that result in physical characters, news studies about the pre-natal diagnostic methods, therapies and treatments, besides the questions involving the social inclusion of the people with DS.