Metabolomics: NMR base genetic diversity

Metabolomics is the systematic identification and quantitation of all metabolites in a givenorganism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR)spectroscopy, allows the simultaneous determination and comparison of thousands of chemical entities,which has lead to an expansion of small molecule biochemistry studies in bacteria, plants, and mammals.Continued development of these analytical platforms will accelerate the widespread use of metabolomicsand allow further integration of small molecules into systems biology.