A Computational Drug Designing From Active Product of Herbal Plant Ochna Squarrosa to Relieve Menstrual Complexities

Ochna squarrosa (Golden Champak), a Bangladeshi herbal plant known locally as Sheuri, has forlong been used for treating menstrual complexities. Although root decoction of the related speciesvariants has been reported to contain active compound Ochnaflavone- a derivative of isoflavonethischemical’s presence in O. squarrosa was far from confirmed. Furhtermore, the molecularmechanism of action of the chemical is yet to be identified. Here, we report the presence ofOchnaflavone in the plant. Moreover, our computational study reveals a plausible target proteinwhere the active compound binds. This study confirms the basis of the traditional herbal practiceand can be useful for further developing a synthetic drug. This in return, we hope, will shift thecurrent use of Ochnaflavone as ‘observational medicine’ to ‘evidence based medicine’.