ANTIBIOTICS SUSCEPTIBILITY OF STAPHYLOCOCCUS AUREUS ISOLATED FROM SOME CLINICAL SAMPLES IN A SECONDARY HEALTH CARE INSTITUTION, NIGERIA

Objective: To investigate the susceptibility of Staphylococcus aureus isolates obtained from clinical samples including urine wound, sputum, stool, high vagina, ear urethral swabs, blood and semen. Methodology: The sensitivity profile of these isolates was determined using the disc diffusion method. Results: Out of 150 samples, 28 (18.7%) yielded S. aureus with the highest isolation from urine (8.7%) and the least from urethra and ear swabs (0.7%). Following the disc diffusion method, the highest sensitivity is recorded for Chloramphenicol (36%) while the least was for Lincocin (7%). Erythromycin, Rifampin, Gentamicin and Ciprofloxacin recorded 18%, 14%, and 11% respectively. Resistance is recorded for Norfloxacin (100%), Streptomycin (100%), Floxapin (100%) and Ampiclox (100%). Conclusion: The studies recommend the use of Chloramphenicol in the treatment of S. aureus infections in the study area. It also underscores the need for susceptibility testing before the administration of antibiotics for the treatment of staphylococcal infections.