INVITRO ANTIPLAETLET ACTIVITY- ETHANOLIC EXTRACT OF RHIZOME OF CURCUMA LONGA LINN

Curcuma longa Linn belongs to the family Zingiberaceae , which is commonly called as turmeric.The traditional report indicates that Curcuma longa Linn is used in the treatment of blood clot.Hence an attempt has been made to screen the effect of Curcuma longa Linn in prevention of platelet aggregation induced by ADP.The ethanolic extract was prepared by continuous hot percolation method. Ethanolic extract was tested in concentration of 62 μg/ml,125 μg/ml,250 μg/ml &500 μg/ml.Aspirin was used as standard.The extract showed comparable antiplatelet activity at 250 μg/ml.The inhibition of platelet aggregation may be due to presence of curcumin in curcuma longa