EVALUATION OF ANTI-HIV-1 ACTIVITY FROM CESTRUM NOCTURNUM AERIAL PARTS AND PHYTOCHEMICAL ANALYSIS

This study deals with evaluation of HIV-1 activity from Cestrum nocturnum aerial partsextracts and investigation of phytoconstituents in the plant extracts. Different extracts fromCestrum nocturnum aerial parts, methanol 80%, ethyl acetate, butanol and aqueous extracts weretested for their anti-HIV-1 activity using the syncytia formation assay. All the extracts wereweak active as anti-HIV-1 agents. Phytochemical analysis of Cestrum nocturnum extracts haveshown the presence of different phytocomponents, saponins, triterpenes and/or sterolsflavonoids, tannins and coumarins. The results confirm that all extracts from Cestrum nocturnumaerial parts have a weak anti-HIV-1 activity.