FEATURES OF IMMUNE STATUS IN UVEITIS HERPESVIRUS ETIOLOGY

Recurrent herpetic uveitis occurring against the backdrop of depression T-mediated immunity, decreased phagocytic activity, accompanied by deficiency of secretory IgA. Observed immune disorders and chronic inflammation is closely associated with impaired cytokine balance and immune cells increased production of proinflammatory cytokines, IL-1β, TNF, IL-6. Virusindutsirovanny immunological disorders characterized by inhibition of the functional activity of cellular immunity, as well as increased levels of CEC with the formation giperimunokompleksnogo syndrome and reduced total compliment. Formation of secondary immunodeficiency syndrome can be viewed as the result of long-term persistence of herpes viruses and the manifestation of chronic intravascular inflammatory pathogenesis associated with uveitis