The induction of T-and B-cells of immune memory during the vaccination with different types of vaccines

The dynamics of the generation of T-and B-cell of immunological memory under the influence of vaccination with different types of vaccines have been investigated. It was found that the creation of resistant strained immunity (The adsorbed diphtheria-tetanus toxin with a reduced amount of antigens, measles vaccine) is associated with a twofold increase during the first months after inoculation of the amount of TCM (CCR7 + CD45RA-) - and BM (CD22 + CD72 +) - memory cells in the peripheral blood. The induction of only memory T-cells (TCM), which is not accompanied by the formation of memory B cells, does not lead to the prolonged preservation of immunity.