MICROBIOLOGICAL AND IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH CHRONIC HYPERPLASTIC DISEASES OF NASOPHARYNX

The main factor in the pathogenesis of chronic inflammation is to reduce the protective properties of the body and the deterioration of the local mucosal immunity. When sowing of the nasopharynx in patients with chronic hyperplastic tonsillitis isolated pyogenic streptococci (S. pyogenes) in 78% of cases, Staphylococcus aureus (S.aureus) - in 67% of cases. Probably, the occurrence of chronic hyperplastic tonsillitis is closely connected with presence on the mucous membrane of the nasopharynx of these microorganisms. To detect violations of the mechanisms of compensation immunological disorders, we measured the content of certain cytokines in the serum of nasopharyngeal swabs, which allowed to investigate the participation of immune cells and their products in the event of activation, and for the development of inflammation of the upper respiratory tract to study the factors contributing to the perpetuation of this group diseases.