Variability of the menstrual cycle in women with regular consuming of cannabis

Marijuana use produces physiological changes which alter the reproductive function. The efects depend on the dose which could lead to a severe depression of the respiratory system. Aim: To know the efects that marijuana exerts on the endocrine function which regulates the menstrual cycle.Material and methods: It has been assessed the hormonal function of 43 pacients who were regular marijuana smokers. They presented menstrual alterations, comparing with a group of non consumer patients who did not undergo hormonal treatment.They were determined by means of radioimmunoassay, estrogens, progesterone, FSH, LH and testosterone.Result: It has been checked that marijuana use dicreases gonadotropins, FHL and LH levels. Estrogens presented similar values to the controled group, being progesterone, testosterone and prolactine values lower than the controled group.The menstrual alteration more frequently detected was the polymenorrhea.