Yellow Nail Syndrome

Yellow Nail Syndrome (YNS)’ is a clinical condition characterized with the yellow colouring of the nails, pleural effusion, bronchectasis, sinusitis, and lymphedema. The ethiology of YNS is unknown. It is widely accepted that this syndrome is originated from an anomaly of the lymphatic vessels and there is no Mendelian inheritance. Male and female ratio is equal. The most significant finding is the yellow colouring of the nails and can be misdiagnosed as fungal infection in some cases. Pleural effusion and sinusitis findings should accompany this condition and can be encountered with some malignant and autoimmune diseases. Nail findings can regress with the treatment of the underlying malignant diseases. Rare cases associated with tuberculosis or myocardial infarction has also been reported. Alpha-tocopherol is reported to be effective in the treatment of YNS in the literature. In this study we present a rare case 40 years old male YNS patient enclosing accompany the syndrome like coughing, shortness of breath, sputum production, stertorous respiration and yellow colouring of the nails.