Floating Drug Delivery Systems: A Review

Purpose of writing this review on floating drug delivery system was to focus on the principle mechanism of floatation to achieve gastric retention. Technological attempts have been made in the research and development of rate controlled oral drug delivery system to overcome physiological adversities, such as short gastric residence time (GRT) and unpredictable gastric emptying times. It is new drug delivery system maximize effectiveness and compliance. This review summarizes advantages of floating drug delivery system approaches to design single unit and multiple unit floating system, in-vitro and in-vivo technology to evaluate the performance of floating system. At attempt has been made in this review article to introduce the readers to current development in floating drug delivery system.