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Cholesterol and Alzheimer's disease

Keywords: treatment , cell biology , ABCA1 , ApoE4 , LRP , LDLR , apolipoprotein , phospholipid , amyloid beta precursor protein , alpha and beta secretase , aggregation and fibril formation , association study , PHF NFT tau phosphorylation , membrane fluidity , statin

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Abstract:

July 26, 2002 featured the conference "Cholesterol and Alzheimer's disease" held at the Biocenter, Frankfurt University, Frankfurt/Maine, Germany. The conference program included ten lectures and eight poster presentations on different aspects of the possible role for cholesterol in Alzheimer's disease and cholesterol neurobiology. This truly international round table event did not aim to come to the consensus but rather to summarize the advances and to discuss directions for near future development. This article presents the abstracts and related bibliography and aims to introduce readers to the multifarious subject of neural cholesterol with special emphasis on Alzheimer's disease and related disorders.

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