Design, synthesis, characterization and biological evaluation of Benzothiazole-6-carboxylate derivatives

A parent benzothiazole molecule was synthesized by Jacobson synthesis, then itis subjected to treatment with various aromatic aldehydes to get the corresponding Schiffbases followed by esterification of carboxyl group by using various alcohols. Thestructures of synthesized compounds were confirmed by various spectroscopic methodssuch as IR, NMR and mass spectroscopy. The products were evaluated for theirantimicrobial activity. Some of the compounds exhibited potent activity when comparedwith the standards.