In vivo effect of casticin on acute inflammation

Objective: To investigate the anti-inflammatory effect of casticin of Fructus Viticis.Methods: Observations were made on the anti-inflammatory effect of casticin in the models of acute inflammation in vivo.Results: Casticin inhibited significantly xylene-induced mouse ear edema, egg albumen-induced rat paw edema and acetic acid-induced mouse vascular permeability.Conclusion: Casticin has significant anti-inflammatory effect on acute inflammation, which is probably related to the inhibition of the inflammation factors. Casticin is the effective constituent contributing to the anti-inflammatory effect of Fructus Viticis