Antimicrobial and Cytotoxic Activity of Actinomycetes From Karwar Coast, West Coast of India

Antibacterial substances from actinomycetes were isolated from marine environment of Karrwar, west coast of India and characterized. Out of the 28 isolates subjected to secondary screening, 12 isolates were active against Bacillus subtilis, 15 against Staphylococcus aureus, 8 against Candida albicans, 3 against Proteus vulgaris and 5 against Salmonella typhi. Metabolites in the extract of Streptomyces spp. culture KR-5, proved to have antimicrobial and cytotoxic against human Breast cancer cell.