Evaluation Of Antibacterial And Antifungal Activity Of Ganoderma Lucidum (Curtis) P. Karst Fruit Bodies Extracts

The present study was carried out to evaluate the antibacterial and antifungal activity of methanol and aqueous extract of fruit bodies from Ganoderma lucidum (Fr.) Karst on selected five bacterial pathogens such as Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus and Streptococcus mutans and five fungal strains Penicillium sps., Aspergillus fumigatous , Aspergillus niger, Aspergillus flavus and Mucour indicus. For antimicrobial test, well diffusion technique was used and the zone of inhibition of microorganisms was measured in mm. The fruit body of G. lucidum showed potential antimicrobial activities against the selected strains and maximum inhibition zone 31mm was recorded from 200mg of aqueous extract of G. lucidum fruit body against Salmonella typhi and Staphylococcus aureus and minimum (10mm) by the Escherichia coli at 50 mg of extract. The methanolic extract showed the maximum antifungal activity 30mm inhibition zone was recorded from 200mg of extract against Mucor indicus and minimum 3mm by 50 mg of extract against Aspergillus flavus.