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The utilization of some coordination compounds of V(IV) and Co(III) as regulators of the content of bioactive substances with antioxidant properties at Spirulina platensisKeywords: cyanobacterium Spirulina platensis , antioxidants , biologically active substances , coordination compounds of V(IV) and Co(III) Abstract: Investigation of non-traditional sources of bioactive substances is one of the current directions of biotechnology development in many countries worldwide. This paper reports on the study of possibility of utilization of some coordination compounds of V(IV) and Co(III) as regulators of the content of bioactive substances with antioxidant properties: superoxiddismutase (SOD), phycobiliproteins, carotenoids and lipids in the biomass of cyanobacterium Spirulina platensis. Natural antioxidants possess a broad spectrum of biological activity due to the ability to neutralize the negative effects of free radicals in living organisms. The obtained experimental results demonstrate that utilization of some coordination compounds of V(IV) at the spirulina cultivation contribute to the accumulation of β-carotene and lipids in spirulina biomass, as well as metallocomplexes of Co(III) have the beneficial effect on the content of phycobiliproteins, lipids and activity of SOD. The present study reveals that obtained biomass of cyanobacterium Spirulina platensis with high content of bioactive substances with antioxidant properties can be used for the elaboration of medical remedies for prophylaxis and treatment of diseases, caused by the negative effect of oxidative stress on live organisms and, also, for the elaboration of cosmetic preparations for the prevention of premature skin aging, protection against solar radiation and treatment of skin diseases.
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