Cellular effects of some bioactive principles from red wines and must

The in vitro action of some samples of red wine and concentrated must on the liver and striated muscle of frog (Rana ridibunda, Pall) was studied, following the intensity of cellular respiration, and the redox potential (rH). Both wine (1 mL/100mL physiological solution normal Ringer – NR) and must (2 mg dry matter/100mL NR) stimulate aerobe cellular respiration (mm3 O2/g wet tissue) and diminish the redox potential values, comparatively with the non-treated reference sample. Also, on treating liver and muscle cells with ethanol (1 mL/100mL NR) an evident depression of cellular respiration and increase of redox potential values may be noticed, alongwith perturbation of cellular metabolic processes. The obtained results evidence possible energizing, hepatoprotecting and redox modulating properties of the bioactive principles from red wine and must.