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Measurement equivalence of the SF-36 in the canadian multicentre osteoporosis studyKeywords: SF-36, Health-related quality of life, Psychometrics, Equivalence, Confirmatory factor analysis Abstract: SF-36 data were from the Canadian Multicentre Osteoporosis Study, a prospective cohort study that randomly sampled adult men and women from nine sites across Canada. Confirmatory factor analysis (CFA) techniques were used to test hypotheses about four forms of ME, which are based on equality of the factor loadings, variances, covariances, and intercepts. Analyses were conducted for Caucasian and non-Caucasian females (n = 6,539) and males (n = 2,884). CFA results revealed that a measurement model with physical and mental health factors provided a good fit to the data. All forms of ME were satisfied for the study groups.The results suggest that sex and race do not influence the conceptualization of a general measure of HRQOL in the Canadian population.The psychometric properties of health-related quality of life (HRQOL) measures and other patient-reported outcomes are an important consideration when undertaking studies in populations with diverse cultural or racial compositions [1]. The Medical Outcomes Study 36-item Short Form Survey (SF-36) is a well-known HRQOL measure used in many countries. While studies have been undertaken about its reliability and validity in different populations [2], its measurement equivalence (ME) properties have not been well examined. ME evaluations seek to answer the question: "Do individuals from different populations interpret a measure in a conceptually similar manner?" [3]. If ME is not tenable, then researchers cannot validly conclude that differences between groups correspond to true population differences because they will be confounded by measurement artifact. Measurement non-equivalence may exist, in part, because study participants do not interpret questions about their health using the same frame of reference [4,5].The purpose of this study is to investigate the ME of the SF-36 by sex and race. We focus on its properties in the Canadian population, where normative data for the SF-36 have now been published [6].Study data wer
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