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Molbank  2013 

2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide

DOI: 10.3390/M800

Keywords: 1,3,4-oxadiazole, pyrazine, S-alkylation, thioether

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Abstract:

S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3 H)-thione ( 3) by 2-chloro- N-(pyrazin-2-yl)acetamide ( 2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}- N-(pyrazin-2-yl)acetamide ( 4). The intermediate ( 2), in turn, was prepared by the acetylation of 2-aminopyrazine ( 1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data.

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