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Quality assessment of total parenteral nutrition admixtures by the use of fractional factorial design

DOI: 10.2298/vsp1304374m

Keywords: parenteral nutrition , particle size , fat emulsions , intravenous , electrolytes , quality control

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Abstract:

Background/Aim. Parenteral nutrition as a specific aspect of providing nutritients still remains a permanent topic of both theoretical and experimental research. Total parenteral nutrition (TPN) admixtures have complex contents making difficult to maintain their stability. The most critical parameter is the diameter of a lipid droplet, i.e. droplet size distribution. It is recommended that droplet size should not be more than 5

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