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Analgesic and antipyretic activity of Curcuma longa rhizome extracts in wister rats

Keywords: Curcuma longa (rhizome) extracts , yield , analgesic , antipyretic , rats , oral

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Abstract:

The study was carried out to ascertain analgesic and antipyretic activities of rhizome extracts of Curcuma longa in Wister rats. Both aqueous and alcoholic extracts at 100 and 200 mg/kg by oral, single dose treatment for seven days revealed significant difference (P<0.05, 0.01) in reaction time in terms of analgesic activity before and after treatments which was comparable to analgin (10 mg/kg b wt.) and were ineffective in reversal of brewers yeast induced pyrexia. Solvent yield of these extracts was 20 percent and color dark brown and reddish brown with solid and semisolid consistency respectively. [Vet World 2009; 2(8.000): 304-306]

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