Classification and grading of canine malignant mammary tumors

Histological grading is a good parameter to stratify tumors according to their biologicalaggressiveness. The Elston and Ellis grading method in humans, invasive ductal breastcarcinomas and other invasive tumors are routinely used. The aims of this study wereclassification of mammary gland tumors and also application of ahuman grading methodincanine mammary carcinoma. The samples included 37 tumors of mammary glands.Mammary tumors were carcinomas (n=32) and sarcomas (n=5). The carcinomas wereclassified as simple carcinoma 56.8% (n= 21), complex carcinoma13.5% (n= 5), carcinomaarising from benign tumor 10.8% (n= 4) and special type of carcinoma 5.4% (n= 2). Out of 32carcinomas studied, 37.5% (n= 12) grade I, 46.9% (n=15) grade II and 15.6% (n= 5) gradeIII. This study demonstrated that the Elston and Ellis method of histological grading in caninemammary tumor is a reliable prognostic factorwhichis correlated with histopathologicalclassification.