Frontal Decision-Making System

Frontal decision making system is both deliberative and authomatic. Cognitive part of this system is mediated by prefrontal areas and emotive by limbyc system and amygdala. Dopaminergic system is important in this function. Th e decision making process is constantly adjusted. Orbitofrontal cortex constantly evaluates the desirability of each action and adjusts decision-making strategy according to the current situation. If the environment is rapidly changing or is uncertain, the anterior cingulate cortex includes in decision-making. Interaction between prefrontal cortex and basal ganglia is necessary for decision-making. Autoactivation is mediated by medial prefrontal cortex and internal palidum. Apathy is a result of disruption of prefrontal decision-making system that consists of prefrontal cortex and prefrontal-subcortical neuronal circuits. Th eory of mind (ToM) describes our ability to understand the mental state of others and to appreciate how it diff ers from our mental state and to predict their behavior. It is believed that the cellular level of ToM are mirror neurons. Impairment of the ToM leads to problems in social relations, providing adequate information, commenting on the conversation, thought disturbance and results in poor communication skills.