Use of image transformation to track the natural history of diseases

Albert SharInformation Technology, Robert Wood Johnson Foundation, Princeton, New Jersey, USAAbstract: The inability to precisely measure the area of a lesion can impair the study of its natural history and response to therapy. This is especially true in case of gastrointestinal lesions, where a standard imaging technique is endoscopy and an unaided visual interpretation of the size of the lesion is difficult. This study presents a novel technique that provides precise measurement of 2-dimensional lesions in cylinder-like organs.Keywords: quantitative endoscopy, Barrett’s esophagus, lesion measurement, disease tracking