Envolvimento sistêmico da doen a periodontal – Quais as consequências?

The periodontal disease (PD) is triggered by a microbial aggression followed by a specific response withlocal and systemic repercussions. Several authors consider DP as a potential risk factor for development of systemicdiseases such as stroke, diabetes, preterm birth, atherosclerosis and cardiovascular diseases. The study of how PD caninfluence a number of systemic disorders is called a periodontal medicine. The biofilm attached in teeth can releasetoxic bacterial products biologically active and the periodontum responds to these substances through the inflammation.There is a varied spectrum of periodontal inflammatory responses to microbial attack, from a slight gingivitis to asevere destructive PD. The bacterial products associated with inflammatory mediators can lead the patient to produce aseries of systemic responses. The purpose of this review is to discuss the possible biological pathways by which the PDcan influence the etiopathogenesis of some diseases and systemic disorders.