Association between childhood trauma and loss of functionality in adult women with fibromyalgia Associa o entre trauma na infancia e perda de funcionalidade em mulheres adultas com fibromialgia

OBJECTIVE: To investigate whether history of childhood trauma is associated with loss of functionality in adult women with fibromyalgia (FM). A secondary objective was to assess the presence of differences between depressed and non-depressed adult women with FM in a regression model for functionality. METHODS: A total of 114 adult women with FM according to the American College of Rheumatology diagnostic criteria answered the Childhood Trauma Questionnaire and the Fibromyalgia Impact Questionnaire. All subjects were interviewed by trained psychiatrists and evaluated for depression using the Mini International Neuropsychiatric Interview (MINI) - Brazilian version 5.0.0. Correlation and regression models were used to investigate associations between childhood trauma and loss of functionality among patients with FM. The sample was stratified by presence and absence of clinical depression. RESULTS: Overall, childhood trauma was associated with of loss of functionality in adult women with FM. When stratified by depression, the regression model significantly increased the association among non-depressed patients, even after adjustment for age and use of psychotropic medications. CONCLUSIONS: Childhood trauma showed a clinically important association with loss of functionality among adult women with FM. The associations were more pronounced among subjects without comorbid depression. OBJETIVO: Investigar se a presen a de história de trauma na infancia está associada com perda de funcionalidade em mulheres adultas com fibromialgia (FM). Um segundo objetivo foi avaliar a presen a de diferen as entre mulheres adultas deprimidas e n o deprimidas com FM utilizando um modelo de regress o para funcionalidade. MéTODOS: Um total de 114 mulheres adultas com FM de acordo com os critérios diagnósticos do American College of Rheumatology responderam o Childhood Trauma Questionnaire e o Questionário de Impacto da Fibromialgia. Todos os indivíduos foram entrevistados por psiquiatras treinados e avaliados para depress o utilizando o Mini International Neuropsychiatric Interview (MINI) - vers o brasileira 5.0.0. Modelos de correla o e regress o foram utilizados para investigar associa es entre trauma na infancia e perda de funcionalidade em pacientes com FM. A amostra foi estratificada pela presen a e ausência de depress o clínica. RESULTADOS: Em geral, o trauma na infancia esteve associado com perda de funcionalidade em mulheres adultas com FM. Quando estratificadas por depress o, o modelo de regress o aumentou significativamente a associa o em pacientes n o deprimidos, me