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Wound healing activity studies of Wrightia arborea Phytosome in rats

Keywords: Wrightia arborea leaves , Incision and Excision wounds , Tensile strength , Epithelization period , WAP , WAET

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Abstract:

Plan: The study was aimed to evaluate the wound healing activity of 70% ethanolic extract (WAET) of the leaves of Wrightia arborea (Apocynaceae) and the phytosome (WAP) prepared out from WAET using incision and excision wound models on wistar albino rats. Methodology: Wound contraction and epithelization period were assessed in excision wound model whereas wound tensile strength was determined in the case of incision wound model. Outcome: The Wrightia arborea phytosome (WAP 4%) exhibited significant wound healing potential when compared to WAET and standard 0.2% Nitrofurazone Ointment.

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