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Significance of recrystallization on pharmaceutical dosage form processing

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Abstract:

Recently in the field of pharmaceutical technology, great efforts are being directed towards the prefabrication of existing drug molecules in the way of solving problems related to poor water solubility, Dissolution, bioavailability, Flowability, compressibility, dosing problem, stability and toxicity.Crystals can be modified by recrystallizing the drug in different ways, which affect the physical and physicochemical properties such as melting point, solubility, true density, dissolution profile, flowability and Tabletability.Recrystallization method is simple and inexpensive enough for scaling up to a commercial level. It reduces time and cost by enabling faster operation, less machinery and fewer personnel. It gives important advances in the different pharmaceutical dosage form technology.Introduction:Recently in the field of pharmaceutical technology, great efforts are being directed towards the prefabrication of existing drug molecules in the way of solving problems related to poor water solubility, bioavailability, Flowability, compressibility, dosing problem, stability and toxicity. 1

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