Oral hypoglycemic agents for treatment of Type-II Diabetes Mellitus : A Review

Diabetes Mellitus (DM) is a chronic disease that is growing in prevalence worldwide. The incidence of each type of diabetes varies widely through out the world.There are more than 125 million persons with diabetes in world today and by 2010: this number is expected to approach 220 Million. Both type 1 and type 2 DM are increasing in frequency. (1) The reason for the increase of type 1 DM is not known .The genetic basis for type 2 DM cannot change in such a short time: thus other contributing factors including age, obesity, sedentary lifestyle, and low birth weight, must account for this drastic increase .In addition type 2 DM is being diagnosed with remarkable frequency preadolescents and adolescents. (2)