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SECONDARY METABOLITE OF Aspergillus fumigatus, ENDOPHYTIC FUNGI OF THE MEDICINAL PLANT Garcinia griffithii

Keywords: Aspergillus fumigatus , endophytic fungi , Garcinia griffithii , secondary metabolite

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Abstract:

The endophytic fungi Aspergillus fumigatus was isolated from the tissues of the fruits of Garcinia griffithii. The fungalstrain was identified from the colony, and it was characteristic of cell morphology. The ethyl acetate extracts derivedfrom fungus cultures showed major spots on TLC under UV light, which was continued to the isolation of thesecondary metabolites. The structure of the isolated compound was elucidated on the basis of NMR analyses (1H-NMR,13C-NMR, HMQC, HMBC and H-H COSY). The compounds were identified as: 4,6-dihydroxy, 3,8a-dimethyl-1-oxo-5-(3’-oxobutan-2’-yl)-1,4,4a,5,6,8a-hexahydronaphthalen-2-yl-1”,2”-dimethyl-5”-(2”’-methylprop-1”’-enyl)cyclopentanecarboxylate.

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