MICROWAVE PROMOTED SUZUKI COUPLINGS OF 2,6-DIBROMO PYRIDINE WITH ARYL BORONIC ACIDS : SYNTHESIS OF MONO AND DIARYL PYRIDINES MICROWAVE PROMOTED Suzuki-Kupplungen von 2,6-DIBROMO PYRIDINE Mit Arylborons uren: Synthese von Mono-und Diaryl PYRIDINE

A simple and general method for the synthesis of symmetrical and unsymmetrical aryl pyridines developed under Microwave irradiation by adopting Suzuki-Miyaura cross couplings. A variety of boronic acids are coupled with 2, 6-dibromo pyridines (1a – h) using Pd[dppf]Cl2 under conventional and Microwave irradiation. Microwave irradiation facilitated reaction course and afforded mono(2a – h) and double coupled(3a – h) products in moderate to high yields in just 15 mins