SILICA SUPPORTED PERCHLORIC ACID: AN EFFICIENT CATALYST FOR THE SYNTHESIS OF CIS-ISOQUINOLONIC ACIDS Siliciumdioxid PERCHLORS URE: AN effizienter Katalysator für die Synthese von cis-ISOQUINOLONIC S UREN

An efficient preparation of cis-isoquinolonic acids employing a one-pot condensation reaction of homopthalic anhydride, aromatic aldehydes and anilines using silica supported perchloric acid is described. Short reaction times, high yields with high purity, mild reaction conditions and recyclability of supported catalyst are the features of this protocol.