SYNTHESIS AND MICROBIAL EVALUATION OF NOVEL TETRAZOLO-TRIAZOLE DERIVATIVES SYNTHESIS und mikrobielle Evaluierung neuartiger Tetrazolo-triazol DERIVATE

5-(4'-Bromomethyl-1, 1'-biphenyl-2-yl) -1H-tetrazole (1) was converted into its azide derivative using sodium azide (2), which on further treatment with malonitrile, diethyl malonate, ethyl acetoacetate and isopropyl acetoacetate to yielded the respective tetrazole-triazole derivatives. The structures of the synthesized compounds were confirmed by Physico-chemical test and spectral techniques, representative samples were screened for their antimicrobial activity against gram positive and gram negative bacteria. Key words: Tetrazoles, Triazoles, Triphenyl phosphine, azides