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OALib Journal期刊
ISSN: 2333-9721
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MICROWAVE ASSISTED SOLVENT-FREE SYNTHESIS OF PYRAZOLO [4,3-C] QUINOLINES USING MONTMORILLONITE K-10 CLAY: AN ENVIRONMENTAL BENIGN APPROACH Mikrowellenunterstützten L SEMITTELFREIE SYNTHESIS von Pyrazolo [4,3-c] Chinoline VERWENDUNG Montmorillonit K-10 CLAY: AN UMWELT Gutartige ANSATZ

Keywords: 4-chloro-quinoline-3-carboxylates , pyrazolo [4 , 3-c] quinolines , Gould-Jacobs reaction , K-10 clay , microwave irradiation.

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Abstract:

A series of novel pyrazolo[4,3-c]quinolines have been synthesized in good to excellent yields by environmental benign solvent free microwave -induced technique involving condensation of ethyl-4-chloroquinoline-3-carboxylates 5 (a-d) with different hydrazines using montmorillonite K-10 clay as a catalyst. All new compounds were characterized by spectral and analytical methods.

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