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Precursor T-Cell acute lymphoblastic leukemia/lymphoma with rare presentation in the urinary bladder

DOI: 10.4081/hr.2011.e18

Keywords: precursor t-cell acute lymphoblastic leukemia/lymphoma , bladder involvement , allogeneic stem cell transplantation

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Abstract:

We present the 16th reported case of Acute Lymphoblastic Leukemia (ALL) with involvement in the bladder. Our patient was a 22 yearold man with T-cell ALL with a mediastinal mass. He received hyperfractionated cyclophosphamide, vincristine, doxorubicin, dexamethasone (HyperCVAD) with mediastinal radiation. Prior to starting maintenance, he relapsed in the bladder and marrow. He received a nelarabine- based induction regimen and achieved remission. This was followed by an unrelated 11/12 HLA-matched myeloablative allogeneic stem cell transplant. He is in complete remission for the past 409 days.

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