Ethnobotanical study, phytochemical characterization and healing effect of Carthamus coeruleus L. rhizomes

Objective of this work is ethnobotanical, phytochemical and healing effect of Carthamus coeruleus (Asteraceae) rhizomes a medicinal plant in the region of Baghlia (Algeria),.The result of ethnobotanical study shows that from 74, 98% of respondents were able to identify 66.66% women aged above 44 years who use this plant frequently for healing and therapy of different degrees’ burns. We conducted a characterization study of rhizomes through a phytochemical screening reveals the presence of alkaloids, leucoanthocyanins, flavonoids, coumarins, saponins and absence of anthocyanins, tannins, and iridoids. To study the healing effect, we chose to formulate healing cream-based Total rhizomes of Cartamus coeruleus with participation of qualified person in this area. This cream was applied to wistar rats in which wounds and burns were caused by incision and burn of 2nd degree, respectively. Healing and cell regeneration of the burnt skin and the wound closure caused, had resulted in the reduction of area. Monitor these areas over time has allowed us evaluation of decreasing diameter for 15 days with a percentage reduction of 85.66% in rats treated with our cream rhizomes Carthamus coeruleus, this being higher than that found in the rats treated with ointments and reference whose value is of 75.12%. The histopathological study has confirmed the effectiveness of the cream prepared by the regeneration of epithelial tissue, which means a good epithelialization of scar tissue.