Antioxidant activity of cissus quadrangularis on sodium perchlorate-induced oxidative damage in rats

The present study was carried out to evaluate the antioxidant activity of flavonoid rich fraction from Cissus quadrangularis(C.Q) Linn on sodium perchlorate induced oxidative stress in rats. Animals were divided into four groups of six animals each. Male Albino rats were fed with 0.2% sodium perchlorate to induce oxidative stress. The flavonoid rich fraction of the plant (1mg/100gm, 2mg/100gm) was administered orally along with sodium perchlorate two groups of animals for 30 days. Animals showed increased antioxidant levels in serum, heart, liver, kidney compared with sodium perchlorate treated group. The results of this study suggest that a flavonoid rich fraction of C.Q has potent antioxidant property. Hence, It could be used as a potential antioxidant agent in the treatment of various diseases.