Choroidal hemodynamics research in patients with diabetes

AIM: To investigate diabetic choroidal hemodynamics in order to provide valuable theories for preventing and treating diabetic retinopathy(DR)and make compensation for the ocular disease of diabetes mellitus(DM). METHODS: Color Doppler flow imaging(CDFI)was used to quantitate peak systolic velocity(PSV), end diastolic velocity(EDV)and resistence index(RI)of the ophthalmic artery(OA), the temporal posterior ciliary artery(PCA1), and nasal posterior ciliary artery(PCA2), in the control group(15 patients)and 45 DM patients. Statistic software was used to analysis the hemodynamic parameters. RESULTS: Relative to the control, the EDV, PSV and RI have changed in non-diabetic retinopathy(NDR), non- proliferative diabetic retinopathy(NPDR)and proliferative diabetic retinopathy(PDR), and the differences are more evident according to the severity of DR. CONCLUSION: We conserved the choroidal circulatory properties of DM. CDFI is very valuable to evaluate the hemodynamic changes in diabetic eyes, and has important significance in the early impression of diabetic choroidopathy.