The oxydative stress as inductive process of toxic action of the Cadmium on the Yeast (Saccharomyces cerevisiae)

As part in evaluation of the impact of the toxicity of heavy metals on the environment, we led a study the behavior of Yeast Saccharomyces cerevisiae towards a xenobiotic and more particularly a heavy metal: the Cadmium on the metabolism energetic. This work concerns the influence of second xenobiotic Zinc applied in treatment combined with cadmium in the presence and / or the absence of calcium on the respiratory activity of Saccharomyces cerevisiae. The obtained results showed inhibition of respiratory activity with an assimilation of oxygen about (52%) to cells treated with the concentrations 5mM and 10mM, whereas the yeast treated with Cd2+ / Ca2+ and Cd2+ / Zn2+ has a respiratory activity with a high consumption of higher oxygen (56%) compared with cells of control. This could possibly show that the activity of detoxification involvement would be dependent energy. Therefore, the measure of respiratory activity shows that the accumulation of Cd can be associated with the oxydative stress reflecting the toxic action of the Cadmium, where from the treatment in the presence of the calcium and / zinc can forbid and reduce its unwanted effects.