EFFECTS OF ALUMINIUM CHLORIDE ON HISTOLOGICAL STRUCTURE OF LUNGS, KIDNEY AND INTESTINE IN PREGNANT RATS AND THEIR OFFSPRING

Chlorure d’aluminium, foetus, intestin, reins, poumons, rates gestantes.Summary: The aim of our study is to elucidate the effects of the administration of different doses of aluminium chloride during 9-13 gestation day on organs histology of pregnant rats and their offspring.We have noted that in pregnant rats, there is a change on the histological structure of intestine especially on enterocytes, nuclei and basal lamina.In kidney, we have observed a lesion in proximal and distal tubes. In lungs, AlCl3 may decrease the alveolar diameter, an inflammation with necrosis of pneumocytes notably with the dose of 200 mg of AlCl3 /kg/day.In fetuses, AlCl3 may cause a detachment between the intestinal epithelium and the underlying conjonctif and a necrosis of renal and pulmonary cells.AlCl3 has an effect more marked in mother than their fetuses. This indicates that the placenta is a selective barrier towards some components.