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OALib Journal期刊
ISSN: 2333-9721
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Synthesis of 4-Thiazolidine Derivatives of 6-Nitroindazole: Pharmaceutical Importance

Keywords: Synthesis , 6-nitroindazole , thiazolidinone , antimicrobial , antitubercular

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Abstract:

New series of N-[3-(1H-6-nitroindazol-1-yl)-propyl]-2-(substituted phenyl)-4-oxo-5-(substitutedbenzylidene)-1,3-thiazolidine-carboxamide, compounds 5(a-j) have been synthesized. Structures of all synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H-NMR, 13C-NMR and FAB-Mass. All the final synthesized compounds 5(a-j) were screened for their antibacterial, antifungal, antitubercular and anti-inflammatory activities.

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